Thromboangiitis obliterans TAO is a segmental inflammatory occlusive disorder that affects small- and medium-sized arteries, and arm and leg veins of young smokers. Several different diagnostic criteria have been offered for the diagnosis of TAO. Clinically, it manifests as migratory thrombophlebitis or signs of arterial insufficiency in the extremities. It is characterized by highly cellular and inflammatory occlusive thrombi, primarily of the distal extremities. Thromboses are often occlusive and sometimes display moderate, nonspecific inflammatory infiltrate, consisting mostly of polymorphonuclear leukocytes, mononuclear cells and rare multinuclear giant cells. The immune system appears to play a critical role in the etiology of TAO.
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Skip to search form Skip to main content You are currently offline. Some features of the site may not work correctly. DOI: Thromboangiitis obliterans TAO is a segmental, inflammatory, vasoocclusive disease that predominantly affects the small and medium-sized arteries and veins of the extremi- ties. It most often occurs in young male smokers, especially those from Mediterranean and Asian countries.
It is consid- ered an autoimmune process related to the use of tobacco products. Clinically, it is characterized by the presence of painful, ischemic ulcers of the digits. View via Publisher. Save to Library. Create Alert.
Launch Research Feed. Share This Paper. Figures and Topics from this paper. Citations Publications citing this paper. Asun Arregui-Murua , J. References Publications referenced by this paper. Intestinal type of thromboangiitis obliterans Buerger's disease.
Sebastian M. Kowal-Gierczak Medicine Angiology Quenneville , Antonio Prat , D. Gossard Medicine Angiology Thrombo-angitis obliterans; a study of the vascular lesions leading to presenile spontaneous gangrene. Thromboangiitis obliterans: classic and new morphological features Akira Kurata , Folker E. Regensburger , H. The changing clinical spectrum of thromboangiitis obliterans Buerger's disease.
Thromboangiitis obliterans. An update on Buerger's disease.
Buerger's disease thromboangiitis obliterans is a nonnecrotizing vasculitis affecting small and medium-sized arteries, typically in young male smokers. The diagnosis can often be made on the basis of a careful history and physical examination, together with ancillary laboratory studies. Occasionally arteriography is warranted to confirm the diagnosis. The pathological findings are distinctive and distinguish this disorder from other arterial occlusive diseases. Successful therapy is possible only with absolute abstinence from tobacco. National Center for Biotechnology Information , U. Journal List West J Med v.
Enfermedad de Buerger (tromboangeítis obliterante)
Important User Information: Remote access to EBSCO's databases is permitted to patrons of subscribing institutions accessing from remote locations for personal, non-commercial use. However, remote access to EBSCO's databases from non-subscribing institutions is not allowed if the purpose of the use is for commercial gain through cost reduction or avoidance for a non-subscribing institution. Source: Informe Medico. Abstract: Tromboangiitis obliterans Leo Buerger disease is associated to the smoking habit.